Abstract
Author(s): AritraChatterjeeand SumanaChatterjee
Coccinia indica, an annual creeper, is available all over India. In the present investigation, petroleum ether extract, 60% methanolic extract and aqueous extracts of the whole plant were made using hot extraction procedure using soxhlet apparatus. The qualitative phyto-chemical screening procedure was performed on each extract. Phyto-chemical study reveals that flavonoid was only present in the methanolic extract. The anti-inflammatory activity of each extract and that of a standard drug, diclofenac sodium were studied using Carageenan induced rat paw oedema model. The extracts and the standard drug were administered orally.It was observed that 60%methanolic extract of Coccinia indicaproduced maximum anti-inflammatory activity even more than the standard drug, diclofenac sodium after 3 hours. Petroleum ether extract and the aqueous extract produced less percentage of inhibition in comparison the standard drug.