Abstract
Author(s): Siddharth R Kamat, Anand H Mane, Sattyanarayan M Arde and Rajashri S Salunkhe*
Environmental safe synthesis of 2-amino-tetrahydro-4H-chromenes in β-Cyclodextrin – glycerinwas achieved by one pot three-component condensation of aromatic aldehydes, malononitrile and dimedone at ambient temperature without the addition of any other catalyst. This synthetic path is inexpensive, efficient, as well as user friendly